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I think it would work as a waterproofer for an enclosure. The only issues I can think of would be related to the Triethoxyoctylsilane. It looks like there was a study performed on rats:
Not sure about how long it will last or if you will have to rebuild for size but make sure you let that sealant outgas all the nasty checmicals in it before you put a human or an animal near it. I'd leave it out in the sun for a week or so